THE MLN8054 DIARIES

Hepatic biotransformation of MLN8054 was analyzed in vitro using human liver S9 fractions (Details on file, Millennium). Glucuronidation of your carboxylate moiety of MLN8054 to an acyl glucuronide was the predominant system of biotransformation, Hydroxylation on the azepine moiety of MLN8054 was the most important period 1 biotransformation pathwa